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Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot. Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press. However, no computer can process the near infinite number of atoms in objects, so instead we model 'finite' groups of them. In the real world, everything that occurs results from the interaction between atoms (and sub-particles of those atoms). If we were to simulate the world in a computer, we would have to simulate this interaction based on the simple laws of physics. Domenico Prattichizzo,, and Antonio Bicchi,"Dynamic "Analysis of Mobility and Graspability of General Manipulation Systems" IEEE transactions on robotics and automation, vol. This paper presents a review of PSO application in Economic Load Dispatch problems. Abstract: Particle swarm optimization (PSO ) is an effective & reliable evolutionary based approach .

Ki "Economic Load Dispatch: A New Hybrid Particle Swarm Optimization Approach"sept.11 2007. Eberhart "Fuzzy Adaptive Particle Swarm Optimization" Evolutionary computation, 2001 proceeding of the 2001 congres on vol.1 page no. Gaing, "Particle Swarm Optimization to solving the economic dispatch considering generator constraints," IEEE Trans. This causes a lot of heat generation and energy loss within the actuators. The study investigates and analyzes the possibilities of reducing the hydraulic resistance and increasing efficiency of the hydraulic actuator.

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